Article

Recommendations of Scrna-Seq Differential Gene Expression Analysis Based on Comprehensive Benchmarking

2022-04-25

Abstract excerpt

To guide analysts to select the right tool and parameters in differential gene expression analysis of single-cell RNA sequencing (scRNA-seq) data, we developed a novel simulator that recapitulates the data characteristics of real scRNA-seq datasets while accounting for all the relevant sources of variation in a multi-subject, multi-condition scRNA-seq experiment: the cell-to-cell variation within a subject, the va...

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Literature Corpus work: bd2612ed-412d-5e74-80ce-797d07315dd4
DOI: 10.20944/preprints202204.0220.v1

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