Article

Detecting differential transcript usage in complex diseases with SPIT

2023-07-10

Abstract excerpt

Differential transcript usage (DTU) plays a crucial role in determining how gene expression differs among cells, tissues, and different developmental stages, thereby contributing to the complexity and diversity of biological systems. In abnormal cells, it can also lead to deficiencies in protein function, potentially leading to pathogenesis of diseases. Detecting such events for single-gene genetic traits is relat...

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Literature Corpus work: 3c7a6085-e990-5ecc-a7c9-3d17c4bc681b
DOI: 10.1101/2023.07.10.548289

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