Article

On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity

2023-10-02

Abstract excerpt

<h4>ABSTRACT</h4> To combat the global burden of malaria, development of new drugs to replace or complement current therapies are urgently required. As drug resistance to existing treatments and clinical failures continue to rise, compounds targeting multiple life cycle stages and species need to be developed as a high priority. Here we show that the compound MMV1557817 is a nanomolar inhibitor of both Plasmodi...

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Literature Corpus work: 3e569e58-a758-59f3-b12f-c96950b0e5e4
DOI: 10.1101/2023.10.01.560396

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