Article

Mapping the substrate sequence and length of the <i>Plasmodium</i> M1 and M17 aminopeptidases

2020-10-13

Abstract excerpt

During malarial infection, Plasmodium parasites digest human hemoglobin to obtain free amino acids for protein production and maintenance of osmotic pressure. The Plasmodium M1 and M17 aminopeptidases are both postulated to have an essential role in the terminal stages of the hemoglobin digestion process and are validated drug targets for the design of new dualtarget anti-malarial compounds. In this study, we pr...

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Literature Corpus work: 277ce9fe-e134-577f-a579-0645957aeca0
DOI: 10.1101/2020.10.13.338178

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