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Genetic and chemical validation of <i>Plasmodium falciparum</i> aminopeptidase <i>Pf</i> A-M17 as a drug target in the hemoglobin digestion pathway

2021-11-23

Abstract excerpt

Plasmodium falciparum, a causative agent of malaria, continues to remain a global health threat since these parasites have developed increasing resistance to all anti-malaria drugs used throughout the world. Accordingly, drugs with novel modes of action are desperately required to combat malaria. P. falciparum parasites infect human red blood cells where they digest the hosts main protein constituent, hemoglobin....

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Identifiers and source

Literature Corpus work
35e89594-bf36-524a-b087-697219dc3040
DOI
10.1101/2021.11.23.469631
Open publication

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