Article

Unsupervized identification of prognostic copy-number alterations using segmentation and lasso regularization

2022-12-16

Abstract excerpt

Identifying copy-number alteration with prognostic impact is typically done in a supervised approach, were candidate regions are user-selected (chomosome arms, oncogenes, etc). Yet CNA events may range from whole chromosome alterations to small focal amplifications or deletions, with no available approach to combine the potential prognostic impact of different aberration ranges. We propose and compare different st...

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Literature Corpus work: 3dcdd7a5-45ad-5d7c-8d70-953582cf226c
DOI: 10.1101/2022.12.14.520497

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