Article
Sequential model selection-based segmentation to detect DNA copy number variation.
Biometrics - 1 Sept 2016
Hu Jianhua, Zhang Liwen, Wang Huixia Judy
Abstract excerpt
Array-based CGH experiments are designed to detect genomic aberrations or regions of DNA copy-number variation that are associated with an outcome, typically a state of disease. Most of the existing statistical methods target on detecting DNA copy number variations in a single sample or array. We focus on the detection of group effect variation, through simultaneous study of multiple samples from multiple groups....
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