Article

GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes

2017-07-06

Abstract excerpt

Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, there is lack of computational methods that systematically detect structural chromosomal aberrations by virtue of the gen...

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Literature Corpus work: 0b0581fd-9ba6-5adf-81e3-1c2a2e735e25
DOI: 10.12688/f1000research.9259.2

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