Article

Robust somatic copy number estimation using coarse-to-fine segmentation

2021-08-08

Abstract excerpt

Cancers routinely exhibit chromosomal instability that results in copy number variants (CNVs), namely changes in the abundance of genomic material. Unfortunately, the detection of these variants in cancer genomes is difficult. We present Ploidetect, a software package that effectively identifies CNVs within whole-genome sequenced tumors. Ploidetect utilizes a coarse-to-fine segmentation approach which yields highl...

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Literature Corpus work: 30e978e2-5d5b-5b26-8c5e-c560da6c83e0
DOI: 10.1101/2021.08.06.455329

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