Article

Short chain fatty acids potentiate azoles by reprogramming fungal acetyl-CoA metabolism

2026-06-30

Abstract excerpt

<h4>ABSTRACT</h4> Pathogens colonise metabolically diverse host environments. How metabolites found in host environments regulate antimicrobial drug susceptibility remains to be fully understood. Here we report on the roles of gut metabolites, short chain fatty acids (SCFAs), in antifungal drug susceptibility of the gut commensal and fungal pathogen Candida albicans . A genetic screen revealed that C. albicans...

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Literature Corpus work: 3d5278db-608b-52d8-b801-6a62a32d242f
DOI: 10.64898/2026.06.29.735392

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