Article

Vitamin B5 Metabolism is Essential for Vacuolar and Mitochondrial Integrity and Xenobiotic Detoxification in Fungi

2023-12-11

Abstract excerpt

<h4>SUMMARY</h4> Fungal infections, a leading cause of mortality among eukaryotic pathogens, pose a growing global health threat due to the rise of drug-resistant strains. New therapeutic strategies are urgently needed to combat this challenge. The PCA pathway for biosynthesis of Co-enzyme A (CoA) and Acetyl-CoA (AcCoA) from vitamin B5 (pantothenic acid) has been validated as an excellent target for the developme...

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Literature Corpus work: e7006f0b-fff4-544a-b021-f3cae7028742
DOI: 10.1101/2023.12.10.571002

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