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Article

Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans.

Eukaryotic cell - 1 Oct 2008

Carman Aaron J, Vylkova Slavena, Lorenz Michael C

Abstract excerpt

Acetyl coenzyme A (acetyl-CoA) is the central intermediate of the pathways required to metabolize nonfermentable carbon sources. Three such pathways, i.e., gluconeogenesis, the glyoxylate cycle, and beta-oxidation, are required for full virulence in the fungal pathogen Candida albicans. These processes are compartmentalized in the cytosol, mitochondria, and peroxosomes, necessitating transport of intermediates...

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Identifiers

PMID: 18689527
DOI: 10.1128/EC.00253-08
PMCID: PMC2568070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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