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The ATO gene family governs Candida albicans colonization in the dysbiotic gastrointestinal tract

3 Sept 2025

Abstract excerpt

ABSTRACT The fungal pathogen Candida albicans colonizes the human gut, where short-chain fatty acids (SCFAs) serve as a source of carbon. This fungus harbors one of the largest microbial families of ATO (acetate transporter ortholog) genes, which encode putative SCFA transport proteins. Here, we generate C. albicans null mutants lacking individual or all known putative SCFA transporter genes and compare their...

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PMID: 40899833
DOI: 10.1128/mbio.01644-25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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