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Article

Long-chain unsaturated fatty acids are involved in the viability and itraconazole susceptibility of Aspergillus fumigatus.

Biochemical and biophysical research communications - 31 Dec 2021

Wang Yuanzhou, Wang Sha, Zeng Liping, Han Ziyu, Cao Jiayi, Wang Yi, Zhong Guowei

Abstract excerpt

The prevalence of invasive aspergillosis with azole resistance is increasing, but the mechanisms underlying the development of resistance and treatment strategies are still limited. The present work is focused on finding a relationship between long-chain unsaturated fatty acids (LCUFAs), Aspergillus fumigatus development, and antifungal resistance. The effects of LCUFAs on antifungal agents in vitro were...

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PMID: 34800884
DOI: 10.1016/j.bbrc.2021.11.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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