Article

Antifungal exposure can enhance <i>Candida glabrata</i> pathogenesis

2025-07-31

Abstract excerpt

Azole antifungal drugs directly inhibit lanosterol 14-ɑ-demethylase and indirectly affect the expression of metabolic, transmembrane transporter, and cell wall organization genes in fungal pathogens. It is not known how these indirect azole effects depend on dose, timing, and specific azole used, or how they influence host interactions. Candida glabrata (recently renamed Nakaseomyces glabratus ) is the second le...

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Literature Corpus work: 1a5c41e7-be90-5307-bdff-3338c21e252c
DOI: 10.1101/2025.07.31.667834

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