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Integration of cell-type resolved spatial proteomics and transcriptomics reveals novel mechanisms in early ovarian cancer

2025-08-28

Abstract excerpt

High-grade serous carcinoma (HGSC) is the most common ovarian cancer subtype, typically diagnosed at late stages with poor prognosis. Understanding early molecular events driving HGSC progression is crucial for timely detection and development of effective treatment strategies. We performed and integrated spatial cell-type resolved proteomics and paired transcriptomics across 25 women with precursor lesions of the...

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Literature Corpus work
3ca5fe41-92b7-57e0-aa50-a697bdd996b8
DOI
10.1101/2025.08.25.25333715
Open publication

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Integration of cell-type resolved spatial proteomics and transcriptomics reveals novel mechanisms in early ovarian cancerDOI 10.1101/2025.08.25.25333715
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