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Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status

26 Aug 2016

Abstract excerpt

A cell line representative of human high-grade serous ovarian cancer (HGSOC) should not only resemble its tumour of origin at the molecular level, but also demonstrate functional utility in pre-clinical investigations. Here, we report the integrated proteomic analysis of 26 ovarian cancer cell lines, HGSOC tumours, immortalized ovarian surface epithelial cells and fallopian tube epithelial cells via a single-run...

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PMID: 27561551
DOI: 10.1038/ncomms12645

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