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3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursors

2025-09-21

Abstract excerpt

<h4>ABSTRACT</h4> Uncovering the spatial and molecular landscape of precancerous lesions is essential for developing meaningful cancer prevention and early detection strategies. High-Grade Serous Carcinoma (HGSC), the most lethal gynecologic malignancy, often originates from Serous Tubal Intraepithelial Carcinomas (STICs) in the fallopian tubes, yet their minute size and our historical reliance on standard 2D his...

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Literature Corpus work
21be6ce3-bd71-5a04-82c5-896044ec0377
DOI
10.1101/2025.09.21.677628
Open publication

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3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursorsDOI 10.1101/2025.09.21.677628
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