Article

Knockout of <i>ykcB</i> , a putative glycosyltransferase, leads to vancomycin resistance in <i>Bacillus subtilis</i>

2022-08-31

Abstract excerpt

<h4>ABSTRACT</h4> Vancomycin resistance of gram-positive bacteria poses a serious health concern around the world. In this study, we searched for vancomycin-resistant mutants from a gene deletion library of a model gram-positive bacterium, Bacillus subtilis , to elucidate the mechanism of vancomycin resistance. We found that knockout of ykcB , a glycosyltransferase that is expected to utilize C55-P-glucose to g...

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Literature Corpus work: 3c6ebe26-c23a-5fb3-9160-2eb507045eba
DOI: 10.1101/2022.08.30.505962

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