Article

Multiple evolutionary pathways lead to vancomycin resistance in <i>Clostridioides difficile</i>

2023-09-15

Abstract excerpt

Clostridioides difficile is an important human pathogen, for which there are very limited treatment options, primarily the glycopeptide antibiotic vancomycin. In recent years vancomycin resistance has emerged as a serious problem in several Gram positive pathogens, but high level resistance has yet to be reported for C. difficile , although it is not known if this is due to constraints upon resistance evolution i...

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Literature Corpus work: 3f54e1b1-49bb-535f-a16b-5eac99f5c5bc
DOI: 10.1101/2023.09.15.557922

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