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Article

The Bacillus subtilis essential gene dgkB is dispensable in mutants with defective lipoteichoic acid synthesis.

Genes & genetic systems - 1 Jan 2011

Matsuoka Satoshi, Hashimoto Michihiro, Kamiya Yusuke, Miyazawa Takeshi, Ishikawa Kazuki, Hara Hiroshi, Matsumoto Kouji

Abstract excerpt

The dgkB gene is essential for the growth of Bacillus subtilis. It encodes a diacylglycerol (DG) kinase that converts DG to phosphatidic acid to reintroduce it into the phospholipid synthesis pathway. Repression of the dgkB gene placed under a regulatable promoter causes accumulation of DG and leads to lethality. DG is formed as a byproduct of the synthesis of lipoteichoic acid (LTA), a polyanionic component of...

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Identifiers

PMID: 22451476
DOI: 10.1266/ggs.86.365

Genes

LTA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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