Article

Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in <i>Clostridioides difficile</i> R20291

2020-11-29

Abstract excerpt

<h4>Summary</h4> Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe that can cause nosocomial antibiotic-associated intestinal disease. Although the production of toxin A (TcdA) and toxin B (TcdB) contribute to the main pathogenesis of C. difficile , the mechanism of TcdA and TcdB release from cell remains unclear. In this study, we identified and characterized a new cell wall h...

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Literature Corpus work: 5187bbf2-1519-5741-83ae-9364aea44796
DOI: 10.1101/2020.11.29.402867

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