Article
Quantitative analysis of the frequency of chromosome loss following DSB induction
2025-01-16
Abstract excerpt
Numerical abnormalities in chromosomal states, referred to as aneuploidy, is commonly observed in many cancer cells. Although numerous internal and external factors induce aneuploidy, the primary cause of aneuploidy in humans remains unclear. DNA damage is identified as a potential cause of aneuploidy by inducing chromosome segregation errors. However, a direct relationship between DNA damage and aneuploidy remain...
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Identifiers and source
- Literature Corpus work
- 3c1263b1-bbac-515a-9dbf-e04714d001dd
- DOI
- 10.1101/2025.01.15.633104