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Article

A selection pressure landscape for 870 human polygenic traits

2020-12-01

Abstract excerpt

<title>Abstract</title> <p>Characterizing the natural selection of complex traits is essential for understanding human evolution and biological or pathological mechanisms. To fulfill this requirement, we leveraged Genome-wide summary statistics for 870 polygenic traits and quantified the selection pressure of different forms and time scales on them in European ancestry. We found that 88% of traits underwent polyg...

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Literature Corpus work
3b72cf19-7da5-5c67-81a8-102ed2067739
DOI
10.21203/rs.3.rs-90125/v1
Open publication

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A selection pressure landscape for 870 human polygenic traitsDOI 10.21203/rs.3.rs-90125/v1
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