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Article

A selection pressure landscape for 870 human polygenic traits.

Nature human behaviour - 1 Dec 2021

Song Weichen, Shi Yueqi, Wang Weidi, Pan Weihao, Qian Wei, Yu Shunying, Zhao Min, Lin Guan Ning

Abstract excerpt

Characterizing the natural selection of complex traits is important for understanding human evolution and both biological and pathological mechanisms. We leveraged genome-wide summary statistics for 870 polygenic traits and attempted to quantify signals of selection on traits of different forms in European ancestry across four periods in human history and evolution. We found that 88% of these traits underwent...

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Share to Databases, Genetic
Share to Genome, Human
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 34782732
DOI: 10.1038/s41562-021-01231-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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