Article

Statistical Mechanical theory for spatio-temporal evolution of Intra-tumor heterogeneity in cancers: Analysis of Multiregion sequencing data

2022-02-20

Abstract excerpt

Variations in characteristics from one region (sub-population) to another is commonly observed in complex systems, such as glasses and a collection of cells. Such variations are manifestations of heterogeneity, whose spatial and temporal behavior is hard to describe theoretically. In the context of cancer, intra-tumor heterogeneity (ITH), characterized by cells with genetic and phenotypic variability that co-exist...

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Literature Corpus work: 3b26fa29-8c05-5875-95cf-f95fb897e5ed
DOI: 10.1101/2022.02.19.481164

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