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Article

The microcosmos of intratumor heterogeneity: the space-time of cancer evolution.

Oncogene - 1 Mar 2020

Janiszewska Michalina

Abstract excerpt

The Cancer Genome Atlas consortium brought us terabytes of information about genetic alterations in different types of human tumors. While many cancer-driver genes have been identified through these efforts, interrogating cancer genomes has also shed new light on tumor complexity. Mutations were found to vary tremendously in their allelic frequencies within the same tumor. Based on those variant allelic...

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Share to Cancer Genomics and Diagnostics
Share to Epigenesis, Genetic
Share to Genes, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31784650
DOI: 10.1038/s41388-019-1127-5
PMCID: PMC7374939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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