Article

Impaired ZNF560 repression during induced pluripotent stem cell reprogramming indicates early epigenetic alterations in Schizophrenia

2026-08-17

Abstract excerpt

Despite extensive epigenetic reprogramming, induced pluripotent stem cells (iPSC) from schizophrenia patients (SZ) retain several molecular and functional features of this disease. Transcriptomic and epigenomic analyses were performed in iPSC of SZ and healthy control subjects (HC). Transcriptional profiles were largely similar between SZ and HC iPSC, whereas pronounced differences emerged following neural differe...

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Literature Corpus work: 3b261434-588e-50d3-bec5-4193778c7a17
DOI: 10.64898/2026.08.14.744920

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