Article

Schizophrenia risk gene ZNF804A controls ribosome localization and synaptogenesis in developing human neurons

2024-02-02

Abstract excerpt

ZNF804A was amongst the first genes robustly associated with schizophrenia based on findings from large-scale genomic studies. Previous research has implicated ZNF804A in the regulation of gene expression and synaptic function, but the role of this gene in neurodevelopment and in schizophrenia pathogenesis remains unclear. To study its function during neurodevelopment, we generated isogenic human induced pluripot...

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Literature Corpus work: 12879489-aa0c-5c30-bbfe-941683bbb842
DOI: 10.1101/2024.02.02.578424

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