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Article

ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2.

PloS one - 1 Jan 2012

Girgenti Matthew J, LoTurco Joseph J, Maher Brady J

Abstract excerpt

ZNF804a was identified by a genome-wide association study (GWAS) in which a single nucleotide polymorphism (SNP rs1344706) in ZNF804a reached genome-wide statistical significance for association with a combined diagnosis of schizophrenia (SZ) and bipolar disorder. Although the molecular function of ZNF804a is unknown, the amino acid sequence is predicted to contain a C2H2-type zinc-finger domain and suggests...

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Identifiers

PMID: 22384243
DOI: 10.1371/journal.pone.0032404
PMCID: PMC3288100

Genes

COMT
PRSS16
DRD2

Provenance

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