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Article

Pancan-meQTL: a database to systematically evaluate the effects of genetic variants on methylation in human cancer.

Nucleic acids research - 8 Jan 2019

Gong Jing, Wan Hao, Mei Shufang, Ruan Hang, Zhang Zhao, Liu Chunjie, Guo An-Yuan, Diao Lixia, Miao Xiaoping, Han Leng

Abstract excerpt

DNA methylation is an important epigenetic mechanism for regulating gene expression. Aberrant DNA methylation has been observed in various human diseases, including cancer. Single-nucleotide polymorphisms can contribute to tumor initiation, progression and prognosis by influencing DNA methylation, and DNA methylation quantitative trait loci (meQTL) have been identified in physiological and pathological contexts....

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Identifiers

PMID: 30203047
DOI: 10.1093/nar/gky814
PMCID: PMC6323988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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