Article
ASMdb: a comprehensive database for allele-specific DNA methylation in diverse organisms.
Nucleic acids research - 7 Jan 2022
Zhou Qiangwei, Guan Pengpeng, Zhu Zhixian, Cheng Sheng, Zhou Cong, Wang Huanhuan, Xu Qian, Sung Wing-Kin, Li Guoliang
Abstract excerpt
DNA methylation is known to be the most stable epigenetic modification and has been extensively studied in relation to cell differentiation, development, X chromosome inactivation and disease. Allele-specific DNA methylation (ASM) is a well-established mechanism for genomic imprinting and regulates imprinted gene expression. Previous studies have confirmed that certain special regions with ASM are susceptible and...
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