Article

PRMT1 mediated methylation of YBX1 promotes tumorigenicity of glioblastoma stem cells

2026-07-16

Abstract excerpt

<title>Abstract</title> <p> Glioblastoma (GBM) is the most lethal primary malignant tumor of the adult central nervous system, with glioblastoma stem cells (GSCs) driving tumor progression, treatment resistance, and relapse. Protein arginine methyltransferase 1 (PRMT1) is aberrantly dysregulated in various cancers and is associated with poor prognosis in glioma; However, the critical substrates and molecular mec...

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Literature Corpus work: 3ae35ef5-0853-5ac3-86df-300b16ebb118
DOI: 10.21203/rs.3.rs-10282905/v1

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