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Elevated YBX1 mRNA expression is associated with a genomically unstable and clinically aggressive cancer state: a pan-cancer analysis

2026-03-23

Abstract excerpt

Y-box binding protein 1 (YB-1; YBX1) is a multifunctional DNA- and RNA-binding protein involved in cell cycle regulation, DNA repair, stress adaptation, and therapy resistance. Elevated YBX1 mRNA expression is associated with aggressive disease across multiple cancers, yet its pan-cancer genomic and clinical correlates remain unclear. Here, we performed a comprehensive pan-cancer analysis across 53 datasets spanni...

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Literature Corpus work
bf88235e-75eb-539f-be50-fe7eb180571a
DOI
10.64898/2026.03.19.712993
Open publication

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Elevated YBX1 mRNA expression is associated with a genomically unstable and clinically aggressive cancer state: a pan-cancer analysisDOI 10.64898/2026.03.19.712993
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