Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic Implications of Targeting YY1 in Glioblastoma

30 May 2024

Abstract excerpt

The transcription factor Yin Yang 1 (YY1) plays a pivotal role in the pathogenesis of glioblastoma multiforme (GBM), an aggressive form of brain tumor. This review systematically explores the diverse roles of YY1 overexpression and activities in GBM, including its impact on the tumor microenvironment (TME) and immune evasion mechanisms. Due to the poor response of GBM to current therapies, various findings of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Ferroptosis and cancer prognosis
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38893192
DOI: 10.3390/cancers16112074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic Implications of Targeting YY1 in GlioblastomaPMID 38893192Read ↗

Yin yang 1: a potential regulator of immune related diseases and cancer immunitySemantic proximity Read ↗

Prognostic significance of YY1 protein expression and mRNA levels by bioinformatics analysis in human cancers: A therapeutic targetSemantic proximity Read ↗

Yin Yang 1 (YY1): Regulation of Survivin and Its Role In Invasion and Metastasis.Semantic proximity Read ↗

A Pan-Cancer Analysis of the Tumorigenic Role of Yin-Yang1 (YY1) in Human TumorsSemantic proximity Read ↗

Dissecting the roles and clinical potential of YY1 in the tumor microenvironmentSemantic proximity Read ↗

miR-186 reverses cisplatin resistance and inhibits the�formation of the glioblastoma-initiating cell�phenotype by degrading Yin Yang 1 in glioblastomaSemantic proximity Read ↗

A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic TargetsSemantic proximity Read ↗

Multifunctional transcription factor YY1: a therapeutic target in human cancer?Semantic proximity Read ↗

YY1 Is a Key Player in Melanoma Immunotherapy/Targeted Treatment ResistanceSemantic proximity Read ↗

Transcription Factor YY1 Contributes to Tumor Growth by Stabilizing Hypoxia Factor HIF-1α in a p53-Independent MannerSemantic proximity Read ↗

YY1 downregulation underlies therapeutic response to molecular targeted agentsSemantic proximity Read ↗

YY1 downregulation underlies therapeutic response to molecular targeted agentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.