Article

Protein arginine-methyltransferase 1 (PRMT1): a new pharmacological target in cholangiocarcinoma

2026-05-29

Abstract excerpt

Cholangiocarcinoma (CCA) is a highly aggressive malignancy characterized by poor prognosis, limited therapeutic options, and a predominantly immunosuppressive tumor microenvironment. Protein arginine methyltransferase 1 (PRMT1), the major mediator of asymmetric arginine dimethylation, has been implicated in multiple oncogenic processes, although its role in CCA remains unknown. Here, we demonstrate that PRMT1 is f...

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Literature Corpus work: 0bc2549b-5440-5109-9619-bdce2ea1a620
DOI: 10.64898/2026.05.29.728163

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