Article

Rubicon modulates neuroimmune responses following traumatic brain injury

2026-03-06

Abstract excerpt

Traumatic brain injury (TBI) elicits robust neuroinflammation and oxidative stress, coupled with an acute inhibition of macro-autophagy (autophagy) in neurons and microglia. Rubicon ( Rubcn ), a Beclin1 interacting protein that suppresses autophagy and mediates LC3-associated phagocytosis and endocytosis (LAP/LANDO), influences inflammatory signaling in metabolic, neurodegenerative, and inflammaging diseases; yet...

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Literature Corpus work: 39b445cf-70c3-5158-9997-c7b6c1e4ff6f
DOI: 10.64898/2026.03.04.709622

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