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Rubicon in Metabolic Diseases and Ageing

10 Jan 2022

Abstract excerpt

Autophagy is a conserved cellular degradation system that maintains intracellular homeostasis. Cytoplasmic components are engulfed into double-membrane vesicles called autophagosomes, which fuse with lysosomes, and resulting in the degradation of sequestered materials. Recently, a close association between autophagy and the pathogenesis of metabolic diseases and ageing has become apparent: autophagy is...

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PMID: 35083223
DOI: 10.3389/fcell.2021.816829

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