Article

Novel structural insights on full-length human RAD52: Cryo-EM and beyond

2023-04-05

Abstract excerpt

Human RAD52 is a DNA-binding protein involved in many DNA repair mechanisms and genomic stability maintenance. In the last few years, this protein was discovered to be a promising novel pharmacological target for anticancer synthetic lethality strategies since its inhibition or modulation, under specific genetic conditions, was proved to enhance therapies efficacy in various cancer cell types. Although the interes...

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Literature Corpus work: 39793f2e-3671-59d0-989d-964f68d2a7cb
DOI: 10.1101/2023.04.03.535362

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Novel structural insights on full-length human RAD52: Cryo-EM and beyondDOI 10.1101/2023.04.03.535362Read

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