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Article

A moving target for drug discovery: Structure activity relationship and many genome (de)stabilizing functions of the RAD52 protein

26 Oct 2022

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36327799
DOI: 10.1016/j.dnarep.2022.103421

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A moving target for drug discovery: Structure activity relationship and many genome (de)stabilizing functions of the RAD52 proteinPMID 36327799Read ↗

Novel structural insights on full-length human RAD52: Cryo-EM and beyondSemantic proximity Read ↗

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Binding of double-strand breaks in DNA by human Rad52 proteinSemantic proximity Read ↗

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Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitorsSemantic proximity Read ↗

Emerging Roles of RAD52 in Genome MaintenanceSemantic proximity Read ↗

Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic AdvancementSemantic proximity Read ↗

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination RepairSemantic proximity Read ↗

Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination.Semantic proximity Read ↗

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Reappearance from Obscurity: Mammalian Rad52 in Homologous RecombinationSemantic proximity Read ↗

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