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Dissecting Complex and Multifactorial Nature of Alzheimer's Disease Pathogenesis: a Clinical, Genomic, and Systems Biology Perspective.

Molecular neurobiology - 1 Sept 2016

Talwar Puneet, Sinha Juhi, Grover Sandeep, Rawat Chitra, Kushwaha Suman, Agarwal Rachna, Taneja Vibha, Kukreti Ritushree

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by loss of memory and other cognitive functions. AD can be classified into familial AD (FAD) and sporadic AD (SAD) based on heritability and into early onset AD (EOAD) and late onset AD (LOAD) based on age of onset. LOAD cases are more prevalent with genetically complex architecture. In spite of significant research focused on...

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PMID: 26351077
DOI: 10.1007/s12035-015-9390-0

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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