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Article

Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease

17 May 2023

Abstract excerpt

Importance: An estimated 40% of dementia is potentially preventable by modifying 12 risk factors throughout the life course. However, robust evidence for most of these risk factors is lacking. Effective interventions should target risk factors in the causal pathway to dementia. Objective: To comprehensively disentangle potentially causal aspects of modifiable risk factors for Alzheimer disease (AD) to inspire new...

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PMID: 37195665
DOI: 10.1001/jamanetworkopen.2023.13734

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