Article

Alzheimer’s Disease-Related Mutations in APP Influence Colorectal Tumor Formation in a Sex-Dependent Manner

2025-11-01

Abstract excerpt

<h4>Summary</h4> Cancer and Alzheimer’s disease (AD) are major age-associated diseases. Numerous studies have indicated common mechanisms and biological interactions between these conditions. Furthermore, epidemiological data demonstrate negative correlations between several cancers and AD. Despite this, few studies have explored their mutual influence on pathological outcomes. We utilized a human APP mutant knoc...

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Literature Corpus work: 39563d94-4497-51d8-bcd2-fc5448581aa2
DOI: 10.1101/2025.10.31.685949

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