Article

An Integrated Germline and Somatic Genomic Model Improves Risk Prediction for Coronary Artery Disease

2024-11-04

Abstract excerpt

Multiple germline and somatic genomic factors are associated with risk of coronary artery disease (CAD), but there is no single measure of risk that integrates all information from a DNA sample, limiting clinical use of genomic information. To address this gap, we developed an integrated genomic model (IGM), analogous to a clinical risk calculator that combines various clinical risk factors into a unified risk est...

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Literature Corpus work: 3930d8fc-0d77-59e6-a0f1-f9825fb42ead
DOI: 10.1101/2024.11.01.24316612

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