Article

Global Knockdown of Glutamate Decarboxylase 67 Elicits Emotional and Auditory Abnormalities in Mice

2020-09-21

Abstract excerpt

<title>Abstract</title> <p>Reduced expression of glutamate decarboxylase 67 (GAD67), encoded by the Gad1 gene, is a consistent finding in postmortem brains of patients with several psychiatric disorders, including schizophrenia, bipolar disorder and major depressive disorder. The dysfunction of GAD67 in the brain is implicated in the pathophysiology of these psychiatric disorders; however, the neurobiological con...

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Literature Corpus work: 3896ad19-f33d-52e0-a1b9-dcf762bef192
DOI: 10.21203/rs.3.rs-78751/v1

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