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Article

Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2015

Fujihara Kazuyuki, Miwa Hideki, Kakizaki Toshikazu, Kaneko Ryosuke, Mikuni Masahiko, Tanahira Chiyoko, Tamamaki Nobuaki, Yanagawa Yuchio

Abstract excerpt

Decreased expression of the GABA synthetic enzyme glutamate decarboxylase 67 (GAD67) in a subset of GABAergic neurons, including parvalbumin (PV)-expressing neurons, has been observed in postmortem brain studies of schizophrenics and in animal models of schizophrenia. However, it is unclear wheth...

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Identifiers

PMID: 25904362
DOI: 10.1038/npp.2015.117
PMCID: PMC4538341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25904362-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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