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Article

Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars.

Proceedings of the National Academy of Sciences of the United States of America - 12 Jun 2007

Benes Francine M, Lim Benjamin, Matzilevich David, Walsh John P, Subburaju Sivan, Minns Martin

Abstract excerpt

GABAergic dysfunction is present in the hippocampus in schizophrenia (SZ) and bipolar disorder (BD). The trisynaptic pathway was "deconstructed" into various layers of sectors CA3/2 and CA1 and gene expression profiling performed. Network association analysis was used to uncover genes that may be related to regulation of glutamate decarboxylase 67 (GAD(67)), a marker for this system that has been found by many...

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Identifiers

PMID: 17553960
DOI: 10.1073/pnas.0703806104
PMCID: PMC1888575

Genes

CCND2
DAXX
GRIK2
HDAC1
PAX5
TLE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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