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Article

Hyperactivity in mice lacking one allele of the glutamic acid decarboxylase 67 gene.

Attention deficit and hyperactivity disorders - 1 Dec 2018

Smith Karen Müller

Abstract excerpt

GABAergic interneuron loss, maturational delay or imbalance of glutamatergic to GABAergic signaling has been implicated in several neuropsychiatric disorders including Tourette syndrome and attention-deficit/hyperactivity disorder (ADHD). In schizophrenia, decreases in parvalbumin (PV), somatostatin (Sst) and glutamic acid decarboxylase (GAD) RNA have been observed and seem to indicate a failure in maturation in...

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Identifiers

PMID: 29556956
DOI: 10.1007/s12402-018-0254-0
PMCID: PMC6146072

Genes

GAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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