Article

MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma

2008-03-31

Abstract excerpt

Summary. The pathogenesis of hepatocellular carcinoma (HCC) is not fully understood, but the majority of patients with HCC are associated with hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. Mannan‐binding lectin (MBL) is a collectin that can act directly as opsonine or activate MBL‐associated serine proteases (MASPs) thus initiating the antibody‐independent pathway of the complement system. In our s...

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Literature Corpus work: 389685f2-62ca-5e8f-856e-658d4cb06101
DOI: 10.1111/j.1365-2893.2008.00965.x

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