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Article

MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma.

Journal of viral hepatitis - 1 May 2008

Segat L, Fabris A, Padovan L, Milanese M, Pirulli D, Lupo F, Salizzoni M, Amoroso A, Crovella S

Abstract excerpt

The pathogenesis of hepatocellular carcinoma (HCC) is not fully understood, but the majority of patients with HCC are associated with hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. Mannan-binding lectin (MBL) is a collectin that can act directly as opsonine or activate MBL-associated serine proteases (MASPs) thus initiating the antibody-independent pathway of the complement system. In our study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18221301
DOI: 10.1111/j.1365-2893.2007.00965.x

Genes

MASP2
MBL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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